With the Exper­i­ment in Ter­ror show find­ing some suc­cess, ama­teur ghost hunters Perry Palomino and Dex Foray embark on their most ter­ri­fy­ing inves­ti­ga­tion yet. A tiny, fog-shrouded island in the rough strait between British Colum­bia and Wash­ing­ton State has held a dark secret for decades: It was a for­mer leper colony where over forty souls were left to rot, die and bury each other. Now a func­tion­ing camp­ground, Perry and Dex spend an iso­lated week­end there to inves­ti­gate poten­tial haunt­ings but as the duo quickly find out, there is more to fear on D’Arcy Island than just ghosts. The island quickly pits part­ner against part­ner, spi­ral­ing the pair into mad­ness that serves to destroy their san­ity, their rela­tion­ship and their very lives.