The Roots Run Deep follows a group of childhood best friends who reunite in their mid-twenties when one of them has a failed suicide attempt. In order to show their struggling friend his life is still worth living, the group decides to embark on an epic road trip that was once a childhood promise. Intertwined with moments throughout their youth that depict the closeness and freedom they once had, the individual battles of adulthood each of them internalize begin to surface. The friends soon realize this trip isn’t for one of them but for all of them.