Recs if you like Prophet, Volume 1: Remission...

These are some of my favorite comic series adapted as graphic novel series that don't come from Marvel or DC and don't involve a bunch of superpowered humans or aliens beating each other up. There is some aliens beating up other aliens in a few of these comics but they're more barfight-level than world-saving fisticuffs.

A posthuman(ish) syllabus - books on or related to posthumanism, transhumanism, cybernetics, autopoiesis, tech, & the (non?)human.

Saga by Brian K Vaughan and Fiona Staples is amazing. And there are a ton of DC and Marvel series that end up on several websites' Best Of Sci-Fi lists. Here are some books that I've loved that I don't see mentioned enough.