John Green, the #1 bestselling author of The Anthropocene Reviewed and a passionate advocate for global healthcare reform, tells a deeply human story illuminating the fight against the world’s deadliest disease. Tuberculosis has been entwined with humanity for millennia. Once romanticized as a malady of poets, today tuberculosis is a disease of poverty that walks the trails of injustice and inequity we blazed for it. In 2019, John Green met Henry, a young tuberculosis patient at Lakka Government Hospital in Sierra Leone while traveling with Partners in Health. John became fast friends with Henry, a boy with spindly legs and a big, goofy smile. In the years since that first visit to Lakka, Green has become a vocal and dynamic advocate for increased access to treatment and wider awareness of the healthcare inequities that allow this curable, treatable infectious disease to also be the deadliest, killing 1.5 million people every year. In Everything is Tuberculosis, John tells Henry’s story, woven through with the scientific and social histories of how tuberculosis has shaped our world and how our choices will shape the future of tuberculosis.

Piranesi’s house is no ordinary building: its rooms are infinite, its corridors endless, its walls are lined with thousands upon thousands of statues, each one different from all the others. Within the labyrinth of halls an ocean is imprisoned; waves thunder up staircases, rooms are flooded in an instant. But Piranesi is not afraid; he understands the tides as he understands the pattern of the labyrinth itself. He lives to explore the house. There is one other person in the house—a man called The Other, who visits Piranesi twice a week and asks for help with research into A Great and Secret Knowledge. But as Piranesi explores, evidence emerges of another person, and a terrible truth begins to unravel, revealing a world beyond the one Piranesi has always known.

At the end of the Second World War, Cyril Conroy combines luck and a single canny investment to begin an enormous real estate empire, propelling his family from poverty to enormous wealth. His first order of business is to buy the Dutch House, a lavish estate in the suburbs outside of Philadelphia. Meant as a surprise for his wife, the house sets in motion the undoing of everyone he loves. The story is told by Cyril’s son Danny, as he and his older sister, the brilliantly acerbic and self-assured Maeve, are exiled from the house where they grew up by their stepmother. The two wealthy siblings are thrown back into the poverty their parents had escaped from and find that all they have to count on is one another. It is this unshakable bond between them that both saves their lives and thwarts their futures. Set over the course of five decades, The Dutch House is a dark fairy tale about two smart people who cannot overcome their past. Despite every outward sign of success, Danny and Maeve are only truly comfortable when they’re together. Throughout their lives, they return to the well-worn story of what they’ve lost with humor and rage. But when at last they’re forced to confront the people who left them behind, the relationship between an indulged brother and his ever-protective sister is finally tested.

From the New York Times-bestselling author of Cutting for Stone comes a stunning and magisterial epic of love, faith, and medicine, set in Kerala, South India, following three generations of a family seeking the answers to a strange secret Spanning the years 1900 to 1977, The Covenant of Water is set in Kerala, on India’s Malabar Coast, and follows three generations of a family that suffers a peculiar affliction: in every generation, at least one person dies by drowning—and in Kerala, water is everywhere. At the turn of the century, a twelve-year-old girl from Kerala's Christian community, grieving the death of her father, is sent by boat to her wedding, where she will meet her forty-year-old husband for the first time. From this unforgettable new beginning, the young girl—and future matriarch, Big Ammachi—will witness unthinkable changes over the span of her extraordinary life, full of joy and triumph as well as hardship and loss, her faith and love the only constants. A shimmering evocation of a bygone India and of the passage of time itself, The Covenant of Water is a hymn to progress in medicine and to human understanding, and a humbling testament to the hardships undergone by past generations for the sake of those alive today. Imbued with humor, deep emotion, and the essence of life, it is one of the most masterful literary novels published in recent years.

Nearly 25 years after Housekeeping, Marilynne Robinson returns with an intimate tale of three generations, from the Civil War to the 20th century: a story about fathers and sons and the spiritual battles that still rage at America's heart. In the words of Kirkus, it is a novel "as big as a nation, as quiet as thought, and moving as prayer. Matchless and towering." GILEAD tells the story of America and will break your heart.

An audacious, darkly glittering novel set in the eerie days of civilization’s collapse—the spellbinding story of a Hollywood star, his would-be savior, and a nomadic group of actors roaming the scattered outposts of the Great Lakes region, risking everything for art and humanity. Kirsten Raymonde will never forget the night Arthur Leander, the famous Hollywood actor, had a heart attack on stage during a production of King Lear. That was the night when a devastating flu pandemic arrived in the city, and within weeks, civilization as we know it came to an end. Twenty years later, Kirsten moves between the settlements of the altered world with a small troupe of actors and musicians. They call themselves The Traveling Symphony, and they have dedicated themselves to keeping the remnants of art and humanity alive. But when they arrive in St. Deborah by the Water, they encounter a violent prophet who will threaten the tiny band’s existence. And as the story takes off, moving back and forth in time, and vividly depicting life before and after the pandemic, the strange twist of fate that connects them all will be revealed.

La joven pintora Yuna Riglos, protagonista de Las primas, regresa en una mujer de casi ochenta años que se regodea en las reminiscencias de un pasado exitoso y en una soledad interrumpida por desencuentros que califica como amistad. Son las "amigas", que llaman a la puerta de su departamento en La Plata, y Yuna comparte con ellas lo que tiene y lo que le falta. Pero será difícil encontrar sentimientos de amistad en esta coreografía de mujeres solitarias movilizadas por la búsqueda de un poco de cariño. "Novela a contrapelo de las buenas intenciones: ni la vejez ni la sororidad son escenarios sencillos de habitar", escribe Liliana Viola en el prólogo a esta edición. Sin embargo, Aurora Venturini, fiel a su estilo, logra una vez más tensar las líneas entre la ficción y el delirio, y atesora la vejez de una Yuna extravagante, egoísta y fuera de toda convención. Las amigas es la novela inédita de Aurora Venturini, un monólogo que comienza a escribir después del éxito de Las primas y en el que siguió trabajando durante años. Tusquets Editores recupera la obra de una de las narradoras fundamentales de la literatura contemporánea.

Hotwired to the leading edges of art and technology, Neuromancer is a cyberpunk, science fiction masterpiece—a classic that ranks with 1984 and Brave New World as one of the twentieth century’s most potent visions of the future. The Matrix is a world within the world, a global consensus-hallucination, the representation of every byte of data in cyberspace... Henry Dorsett Case was the sharpest data-thief in the business, until vengeful former employees crippled his nervous system. But now a new and very mysterious employer recruits him for a last-chance run. The target: an unthinkably powerful artificial intelligence orbiting Earth in service of the sinister Tessier-Ashpool business clan. With a dead man riding shotgun and Molly, mirror-eyed street-samurai, to watch his back, Case embarks on an adventure that ups the ante on an entire genre of fiction. The winner of the Hugo, Nebula, and Philip K. Dick Awards, Neuromancer was the first fully-realized glimpse of humankind’s digital future—a shocking vision that has challenged our assumptions about our technology and ourselves, reinvented the way we speak and think, and forever altered the landscape of our imaginations.

Prepare to be hooked - pre-order the unputdownable new thriller from No.1 Sunday Times bestseller Andrea Mara.Look what you started.You press send. Your message is full of secrets about your neighbours. It’s meant for your sister, but it doesn’t reach her – it goes to the entire local community WhatsApp group instead.Now everyone knows what you did.As rumour spreads like wildfire through the picture-perfect neighbourhood, you convince yourself that people will move on, that this will quickly be forgotten. But then you receive the first death threat.And someone wants you dead.The next day, a woman has been murdered. And what’s even more chilling is that she had the same address as you – 26 Oakpark – but in a different part of town. Did the killer get the wrong house? It won’t be long before you find out…

‘This story of a woman’s survival after the worst has happened, makes for a searingly beautiful novel.’ Jennie Godfrey, author of The List of Suspicious Things ‘Exceptional . . . simply an exquisite novel’ Anne Griffin, author of When All Is Said How do you survive the unsurvivable? Rachel lives with her husband Tom and their two children: it's the ordinary family life she always thought she'd have. All of that changes in an instant - when Tom runs the family car off the road, seeking to end his own life, and take his wife and children with him. Rachel is left to pore over the wreckage to try and understand what happened - to find a way to go on living afterwards. What emerges is a snapshot of what it's like to live alongside someone who is suffering, how you keep yourself afloat when the person you love is drowning, and how you survive irreparable loss. Impossible to turn away from, Show Me Where It Hurts is a compelling, heartbreaking and ultimately life-affirming story of recovery and unexpected hope.