Appalachia has played a complex and often contradictory role in the unfolding of American history. Created by urban journalists in the years following the Civil War, the idea of Appalachia provided a counterpoint to emerging definitions of progress. Early-twentieth-century critics of modernity saw the region as a remnant of frontier life, a reflection of simpler times that should be preserved and protected. However, supporters of development and of the growth of material production, consumption, and technology decried what they perceived as the isolation and backwardness of the place and sought to "uplift" the mountain people through education and industrialization. Ronald D Eller has worked with local leaders, state policymakers, and national planners to translate the lessons of private industrial-development history into public policy affecting the region. In Uneven Ground: Appalachia since 1945, Eller examines the politics of development in Appalachia since World War II with an eye toward exploring the idea of progress as it has evolved in modern America. Appalachia's struggle to overcome poverty, to live in harmony with the land, and to respect the diversity of cultures and the value of community is also an American story. In the end, Eller concludes, "Appalachia was not different from the rest of America; it was in fact a mirror of what the nation was becoming."

From the New York Times best-selling author of Stiff and Fuzz, a rollicking exploration of the quest to re-create the impossible complexities of human anatomy. The body is the most complex machine in the world, and the only one for which you cannot get a replacement part from the manufacturer. For centuries, medicine has reached for what’s available—sculpting noses from brass, borrowing skin from frogs and hearts from pigs, crafting eye parts from jet canopies and breasts from petroleum by-products. Today we’re attempting to grow body parts from scratch using stem cells and 3D printers. How are we doing? Are we there yet? In Replaceable You, Mary Roach explores the remarkable advances and difficult questions prompted by the human body’s failings. When and how does a person decide they’d be better off with a prosthetic than their existing limb? Can a donated heart be made to beat forever? Can an intestine provide a workable substitute for a vagina? Roach dives in with her characteristic verve and infectious wit. Her travels take her to the OR at a legendary burn unit in Boston, a “superclean” xeno-pigsty in China, and a stem cell “hair nursery” in the San Diego tech hub. She talks with researchers and surgeons, amputees and ostomates, printers of kidneys and designers of wearable organs. She spends time in a working iron lung from the 1950s, stays up all night with recovery techs as they disassemble and reassemble a tissue donor, and travels across Mongolia with the cataract surgeons of Orbis International. Irrepressible and accessible, Replaceable You immerses readers in the wondrous, improbable, and surreal quest to build a new you.

A remarkable story of the scientists behind a long-forgotten and life-saving the healing viruses that can conquer antibiotic resistant bacterial infectionsFirst discovered in 1917, bacteriophages—or “phages”—are living viruses that devour bacteria. Ubiquitous in the environment, they are found in water, soil, inside plants and animals, and in the human body.When phages were first recognized as medicines, their promise seemed limitless. Grown by research scientists and physicians in France, the Soviet Union, and elsewhere to target specific bacteria, they cured cholera, dysentery, bubonic plague, and other deadly infectious diseases.But after Stalin’s brutal purges and the rise of antibiotics, phage therapy declined and nearly was lost to history—until today. In The Living Medicine, acclaimed science journalist Lina Zeldovich reveals the remarkable history of phages, told through the lives of the French, Soviet, and American scientists who discovered, developed, and are reviving this unique cure for seemingly-intractable diseases. Ranging from Paris to Soviet Georgia to Egypt, India, South Africa, remote islands in the Far East, and America, The Living Medicine shows how phages once saved tens of thousands of lives. Today, with our antibiotic shield collapsing, Zeldovich demonstrates how phages are making our food safe and, in cases of dire emergency, rescuing people from the brink of death. They may be humanity’s best defense against the pandemics to come.Filled with adventure, human ambition, tragedy, technology, irrepressible scientists and the excitement of their innovation, The Living Medicine offers a vision of how our future may be saved by knowledge from the past.

The newest edition is here. Another alternate cover can be found here. Emma Woodhouse is one of Austen's most captivating and vivid characters. Beautiful, spoilt, vain and irrepressibly witty, Emma organizes the lives of the inhabitants of her sleepy little village and plays matchmaker with devastating effect.

The serene and maternal Mrs. Ramsay, the tragic yet absurd Mr. Ramsay, and their children and assorted guests are on holiday on the Isle of Skye. From the seemingly trivial postponement of a visit to a nearby lighthouse, Woolf constructs a remarkable, moving examination of the complex tensions and allegiances of family life and the conflict between men and women. As time winds its way through their lives, the Ramsays face, alone and simultaneously, the greatest of human challenges and its greatest triumph—the human capacity for change.

Written in 1914 but not published until 1925, a year after Kafka’s death, The Trial is the terrifying tale of Josef K., a respectable bank officer who is suddenly and inexplicably arrested and must defend himself against a charge about which he can get no information. Whether read as an existential tale, a parable, or a prophecy of the excesses of modern bureaucracy wedded to the madness of totalitarianism, The Trial has resonated with chilling truth for generations of readers.

Bill Bryson describes himself as a reluctant traveller, but even when he stays safely at home he can't contain his curiosity about the world around him. "A Short History of Nearly Everything" is his quest to understand everything that has happened from the Big Bang to the rise of civilisation - how we got from there, being nothing at all, to here, being us. The ultimate eye-opening journey through time and space, revealing the world in a way most of us have never seen it before.

Six days ago, astronaut Mark Watney became one of the first people to walk on Mars. Now, he’s sure he’ll be the first person to die there. After a dust storm nearly kills him and forces his crew to evacuate while thinking him dead, Mark finds himself stranded and completely alone with no way to even signal Earth that he’s alive—and even if he could get word out, his supplies would be gone long before a rescue could arrive. Chances are, though, he won’t have time to starve to death. The damaged machinery, unforgiving environment, or plain-old “human error” are much more likely to kill him first. But Mark isn’t ready to give up yet. Drawing on his ingenuity, his engineering skills — and a relentless, dogged refusal to quit — he steadfastly confronts one seemingly insurmountable obstacle after the next. Will his resourcefulness be enough to overcome the impossible odds against him?